TIMTEC-BB SBB006527
Ranitidine
CAS: 66357-35-5
Molecular Formula: C13H22N4O3S
TIMTEC-BB SBB006527 - Names and Identifiers
| Name | Ranitidine |
| Synonyms | Sostril 266-332-5 RANITIDINE Ranitidine RANITIDINE BASE Ranitidine base TIMTEC-BB SBB006527 1,1-ethenediamine,n-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)eth N'-Methyl-N-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]-2-nitro-1-ethenediarnine 1,1-ethenediamine, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro- 1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N'-methyl-2-nitro- 1,1-Ethenediamine, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro- (E)-N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine N-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine (E)-N-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine (Z)-N-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine |
| CAS | 66357-35-5 |
| EINECS | 266-332-5 |
| InChI | InChI=1/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+ |
TIMTEC-BB SBB006527 - Physico-chemical Properties
| Molecular Formula | C13H22N4O3S |
| Molar Mass | 314.4 |
| Density | 1.184±0.06 g/cm3(Predicted) |
| Melting Point | 69-70°C |
| Boling Point | 437.1±45.0 °C(Predicted) |
| Flash Point | 218.2°C |
| Water Solubility | 24.7 mg/mL |
| Solubility | H2O: 1.8mg/mL |
| Vapor Presure | 7.66E-08mmHg at 25°C |
| Appearance | solid |
| Color | tan |
| pKa | pKa 2.19±0.04 (Uncertain) |
| Storage Condition | Desiccate at +4°C |
| Stability | Hygroscopic |
| Refractive Index | 1.558 |
| Physical and Chemical Properties | Solid, melting point 69-70 °c. Ranitidine Hydrochloride: C13 H22N4O3S? HCI. [66357-59-3]. Off-white or pale yellow crystalline powder, with peculiar odor, slightly bitter and astringent taste. Easy to absorb moisture. Soluble in methanol or water or acetic acid, slightly soluble in ethanol, a few do not dissolve in chloroform or acetone. Melting Point 137-143 °c (decomposition). Melting point 133-134 °c (Merck Index 12th). |
| Use | Digestive system medication, used to relieve stomach pain, heartburn, acid reflux, etc. |
TIMTEC-BB SBB006527 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 2 |
| RTECS | KM6557000 |
| Toxicity | LD50 oral in rat: > 5gm/kg |
TIMTEC-BB SBB006527 - Nature
Open Data Verified Data
Solid, melting point 69-70 °c.
Last Update：2024-01-02 23:10:35
TIMTEC-BB SBB006527 - Preparation Method
Open Data Verified Data
5-[(dimethylamino) methyl]-2-furazolcarbinol reacts with cysteine to produce 2-[[5-(dimethylamino)] methyl -2-furyl] methyl] Thio] ethylamine. Dissolve n-methyl-1-methylthio-2-nitrovinylmethylamine in water, heat and stir, drop the substance obtained from the surface, react for a certain time, add 4-methyl -2-pentanone, ranitidine was obtained after further treatment.
Last Update：2022-01-01 09:22:53
TIMTEC-BB SBB006527 - Use
Open Data Verified Data
histamine H: receptor antagonist. It can effectively inhibit the gastric acid secretion caused by basal gastric acid and gastrin stimulation, and reduce the activity of gastric acid and gastric enzyme. The effect is 5~8 times stronger than cimetidine, and the maintenance time is long, and there is no adverse reaction of cimetidine on the central nervous system, gonad and so on. It is mainly used for the treatment of active gastric and duodenal ulcer, reflux esophagitis, Zhuoyi AI syndrome and other high gastric acid secretion diseases, acute gastric mucosal damage and non-steroidal anti-inflammatory drugs (including aspirin) in stress state. Caused by acute gastric mucosal injury, general anesthesia or after major surgery and debilitating Coma patients to prevent acid reflux and aspiration pneumonia.
Last Update：2022-01-01 09:22:53
Supplier List
Product Name: Ranitidine Monomer Request for quotation
CAS: 66357-35-5
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CAS: 66357-35-5
Tel: 0714-3999186
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Product Name: Ranitidine Monomer Request for quotation
CAS: 66357-35-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 66357-35-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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